Human Gene Set: GOCC_SM_LIKE_PROTEIN_FAMILY_COMPLEX

For the Mouse gene set with the same name, see GOCC_SM_LIKE_PROTEIN_FAMILY_COMPLEX

Standard name GOCC_SM_LIKE_PROTEIN_FAMILY_COMPLEX
Systematic name M26033
Brief description A protein complex containing members of the Like-Sm family of proteins, which includes both the Sm proteins and the Lsm proteins, and which generally form hexameric or heptameric ring structures which bind to RNA. While some of these ring complexes may form independently of RNA, many only form in association with their target RNA. In addition to Lsm-family proteins, many of these complexes contain additional protein members. Members of this family of complexes include the snRNPs which comprise the majority of the spliceosome. Others are involved in the 5' to 3' degradation pathways of mRNAs in the cytoplasm and of unspliced transcripts in the nucleus, as well as other diverse roles. [GOC:bhm, GOC:krc, PMID:19121818, PMID:27627834]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:0120114
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0120114
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references  
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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Version history 2024.1.Hs: Updated to GO Release 2024-04-24.

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