Human Gene Set: GOCC_SMC5_SMC6_COMPLEX
For the Mouse gene set with the same name, see GOCC_SMC5_SMC6_COMPLEX
Standard name
GOCC_SMC5_SMC6_COMPLEX
Systematic name
M43109
Brief description
A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans. [GOC:rb, PMID:14701739, PMID:15738391, PMID:27373152]
Full description or abstract
Collection
C5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component
Source publication
Exact source
GO:0030915
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0030915
Filtered by similarity ?
Source species
Homo sapiens
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Human_NCBI_Gene_ID
Dataset references
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NCI-60 cell lines (National Cancer Institute)
Advanced query
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these 9 genes
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9 genes by gene family
Show members
(show 9 source identifiers mapped to 9 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
197370
197370
NSMCE1
NSE1 homolog, SMC5-SMC6 complex component [...
23137
23137
SMC5
structural maintenance of chromosomes 5 [So...
286053
286053
NSMCE2
NSE2 (MMS21) homolog, SMC5-SMC6 complex SUM...
493861
493861
EID3
EP300 interacting inhibitor of differentiat...
54780
54780
NSMCE4A
NSE4 homolog A, SMC5-SMC6 complex component...
55719
55719
SLF2
SMC5-SMC6 complex localization factor 2 [So...
56160
56160
NSMCE3
NSE3 homolog, SMC5-SMC6 complex component [...
79677
79677
SMC6
structural maintenance of chromosomes 6 [So...
84250
84250
SLF1
SMC5-SMC6 complex localization factor 1 [So...
Version history
2024.1.Hs: Updated to GO Release 2024-04-24.
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