Human Gene Set: GOCC_SIN3_TYPE_COMPLEX

For the Mouse gene set with the same name, see GOCC_SIN3_TYPE_COMPLEX

Standard name GOCC_SIN3_TYPE_COMPLEX
Systematic name M17413
Brief description Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1 and HDAC2 in mammals), and at least one WD40 repeat protein (e.g. Ume1p in S. cerevisiae, Prw1 in S. pombe, or RbAp46 and RbAp48 in mammals). These complexes also contain a variable number of other proteins that direct histone binding, DNA binding, or add other functionality to the complex. [PMID:15565322, PMID:18292778]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:0070822
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0070822
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
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GTEx compendium
Human tissue compendium (Novartis)
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NCI-60 cell lines (National Cancer Institute)
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Version history 2024.1.Hs: Updated to GO Release 2024-04-24.

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