Human Gene Set: GOCC_SCF_UBIQUITIN_LIGASE_COMPLEX

For the Mouse gene set with the same name, see GOCC_SCF_UBIQUITIN_LIGASE_COMPLEX

Standard name GOCC_SCF_UBIQUITIN_LIGASE_COMPLEX
Systematic name M17110
Brief description A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1). [PMID:15571813, PMID:15688063]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:0019005
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0019005
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
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Version history 2026.1.Hs: Updated to GO Release 2025-10-10.


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