Human Gene Set: GOCC_PYRUVATE_DEHYDROGENASE_COMPLEX

For the Mouse gene set with the same name, see GOCC_PYRUVATE_DEHYDROGENASE_COMPLEX

Standard name GOCC_PYRUVATE_DEHYDROGENASE_COMPLEX
Systematic name M48592
Brief description A multi-enzyme complex that catalyzes the oxidative decarboxylation of pyruvate to form acetyl-CoA. The complex comprises multiple copies of three enzymes referred to as E1, E2 and E3: pyruvate dehydrogenase (E1, which may be a homodimer or a heterotetramer of two alpha and two beta subunits, depending on species), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Additional proteins may also be present. [PMID:36863425]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:0045254
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0045254
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
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Version history 2026.1.Hs: Updated to GO Release 2025-10-10.


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