Human Gene Set: GOCC_PRP19_COMPLEX
For the Mouse gene set with the same name, see GOCC_PRP19_COMPLEX
Standard name
GOCC_PRP19_COMPLEX
Systematic name
M17498
Brief description
A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p. [GOC:krc, PMID:16540691, PMID:19239890]
Full description or abstract
Collection
C5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component
Source publication
Exact source
GO:0000974
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0000974
Filtered by similarity ?
Source species
Homo sapiens
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Human_NCBI_Gene_ID
Dataset references
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Advanced query
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these 14 genes
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14 genes by gene family
Show members
(show 14 source identifiers mapped to 14 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
10286
10286
BCAS2
BCAS2 pre-mRNA processing factor [Source:HGNC...
11338
11338
U2AF2
U2 small nuclear RNA auxiliary factor 2 [Sour...
25949
25949
SYF2
SYF2 pre-mRNA splicing factor [Source:HGNC Sy...
27339
27339
PRPF19
pre-mRNA processing factor 19 [Source:HGNC Sy...
3312
3312
HSPA8
heat shock protein family A (Hsp70) member 8 ...
51340
51340
CRNKL1
crooked neck pre-mRNA splicing factor 1 [Sour...
51503
51503
CWC15
CWC15 spliceosome associated protein homolog ...
5356
5356
PLRG1
pleiotropic regulator 1 [Source:HGNC Symbol;A...
5430
5430
POLR2A
RNA polymerase II subunit A [Source:HGNC Symb...
55696
55696
RBM22
RNA binding motif protein 22 [Source:HGNC Sym...
56259
56259
CTNNBL1
catenin beta like 1 [Source:HGNC Symbol;Acc:H...
56949
56949
XAB2
XPA binding protein 2 [Source:HGNC Symbol;Acc...
57461
57461
ISY1
ISY1 splicing factor homolog [Source:HGNC Sym...
988
988
CDC5L
cell division cycle 5 like [Source:HGNC Symbo...
Version history
2024.1.Hs: Updated to GO Release 2024-04-24.
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