Human Gene Set: GOCC_PHOSPHATIDYLINOSITOL_3_KINASE_COMPLEX_CLASS_I
For the Mouse gene set with the same name, see GOCC_PHOSPHATIDYLINOSITOL_3_KINASE_COMPLEX_CLASS_I
Standard name
GOCC_PHOSPHATIDYLINOSITOL_3_KINASE_COMPLEX_CLASS_I
Systematic name
M25964
Brief description
A phosphatidylinositol 3-kinase complex that contains a catalytic and a regulatory subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme, plus one or more adaptor proteins. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. The class I PI3K subfamily of genes comprises members in vertebrates, worm and fly, but none in yeast. [GOC:ha, PMID:24587488]
Full description or abstract
Collection
C5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component
Source publication
Exact source
GO:0097651
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0097651
Filtered by similarity ?
(show 1 similar ontology term(s) from the external resource)
External ID
External Name
GO:0005943
phosphatidylinositol 3-kinase complex, class IA
Source species
Homo sapiens
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Human_NCBI_Gene_ID
Dataset references
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these 9 genes
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9 genes by gene family
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(show 9 source identifiers mapped to 9 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
146850
146850
PIK3R6
phosphoinositide-3-kinase regulatory subunit...
23533
23533
PIK3R5
phosphoinositide-3-kinase regulatory subunit...
5290
5290
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kina...
5291
5291
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kina...
5293
5293
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kina...
5294
5294
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kina...
5295
5295
PIK3R1
phosphoinositide-3-kinase regulatory subunit...
5296
5296
PIK3R2
phosphoinositide-3-kinase regulatory subunit...
8503
8503
PIK3R3
phosphoinositide-3-kinase regulatory subunit...
Version history
2024.1.Hs: Updated to GO Release 2024-04-24.
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