Human Gene Set: GOCC_PERINUCLEAR_THECA

For the Mouse gene set with the same name, see GOCC_PERINUCLEAR_THECA

Standard name GOCC_PERINUCLEAR_THECA
Systematic name M43116
Brief description A condensed cytoplasmic structure that covers the nucleus of mammalian spermatozoa except for a narrow zone around the insertion of the tail. It shows two distinct regions, a subacrosomal layer and, continuing caudally beyond the acrosomic system, the postacrosomal sheath. The perinuclear theca has been considered a cytoskeletal scaffold responsible for maintaining the overall architecture of the mature sperm head; however, recent studies indicate that the bulk of its constituent proteins are not traditional cytoskeletal proteins but rather a variety of cytosolic proteins. [PMID:17289678, PMID:8025156]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:0033011
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0033011
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
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Version history 2026.1.Hs: Updated to GO Release 2025-10-10.


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