Human Gene Set: GOCC_MKS_COMPLEX
For the Mouse gene set with the same name, see GOCC_MKS_COMPLEX
Standard name
GOCC_MKS_COMPLEX
Systematic name
M25814
Brief description
A protein complex that is located at the ciliary transition zone and consists of several proteins some of which are membrane bound. Acts as an organiser of transition zone inner structure, specifically the Y-shaped links, in conjunction with the NPHP complex. The MKS complex also acts as part of the selective barrier that prevents diffusion of proteins between the ciliary cytoplasm and cellular cytoplasm as well as between the ciliary membrane and plasma membrane. [GOC:cilia, GOC:sp, PMID:21422230, PMID:21565611, PMID:21725307, PMID:22179047, PMID:25869670, PMID:26595381, PMID:26982032]
Full description or abstract
Collection
C5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component
Source publication
Exact source
GO:0036038
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0036038
Filtered by similarity ?
Source species
Homo sapiens
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Human_NCBI_Gene_ID
Dataset references
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Advanced query
Further investigate
these 13 genes
Gene families ?
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13 genes by gene family
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(show 13 source identifiers mapped to 13 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
200728
200728
TMEM17
transmembrane protein 17 [Source:HGNC Symbo...
27077
27077
B9D1
B9 domain containing 1 [Source:HGNC Symbol;...
51259
51259
TMEM216
transmembrane protein 216 [Source:HGNC Symb...
54806
54806
AHI1
Abelson helper integration site 1 [Source:H...
54903
54903
MKS1
MKS transition zone complex subunit 1 [Sour...
57545
57545
CC2D2A
coiled-coil and C2 domain containing 2A [So...
79583
79583
TMEM231
transmembrane protein 231 [Source:HGNC Symb...
79600
79600
TCTN1
tectonic family member 1 [Source:HGNC Symbo...
79867
79867
TCTN2
tectonic family member 2 [Source:HGNC Symbo...
80184
80184
CEP290
centrosomal protein 290 [Source:HGNC Symbol...
80776
80776
B9D2
B9 domain containing 2 [Source:HGNC Symbol;...
84314
84314
TMEM107
transmembrane protein 107 [Source:HGNC Symb...
91147
91147
TMEM67
transmembrane protein 67 [Source:HGNC Symbo...
Version history
2024.1.Hs: Updated to GO Release 2024-04-24.
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