Human Gene Set: GOCC_MHC_CLASS_I_PEPTIDE_LOADING_COMPLEX

For the Mouse gene set with the same name, see GOCC_MHC_CLASS_I_PEPTIDE_LOADING_COMPLEX

Standard name GOCC_MHC_CLASS_I_PEPTIDE_LOADING_COMPLEX
Systematic name M25832
Brief description A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules. [GOC:jl, PMID:10631934]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:0042824
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0042824
Filtered by similarity ?
Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 8 genes
Gene families ? Categorize these 8 genes by gene family
Show members (show 8 source identifiers mapped to 8 genes)
Version history 2024.1.Hs: Updated to GO Release 2024-04-24.

See MSigDB license terms here. Please note that certain gene sets have special access terms.