The region of a kinetochore closest to centromeric DNA which contains many CENP proteins organized in various subcomplexes including CENP-C, CENP-LN, CENP-HIKM, CENP-OPQUR and CENP-TWSX, but excluding the CENP-A containing heterochromatin. [GOC:clt, PMID:10619130, PMID:11483983, PMID:32516549]
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C5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component