Human Gene Set: GOCC_GATOR2_COMPLEX
For the Mouse gene set with the same name, see GOCC_GATOR2_COMPLEX
Standard name
GOCC_GATOR2_COMPLEX
Systematic name
M25880
Brief description
A multiprotein subcomplex of the GATOR complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, this complex consists of WDR24, WDR59, MIOS, SEH1L, and SEC13. In S. cerevisiae, this complex is referred to as SEACAT and contains the Sea2p, Sea3p, Sea4p, Seh1p, Sec13p proteins. [GOC:krc, GOC:rb, PMID:23723238, PMID:25934700]
Full description or abstract
Collection
C5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component
Source publication
Exact source
GO:0061700
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0061700
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Source species
Homo sapiens
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Human_NCBI_Gene_ID
Dataset references
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NCI-60 cell lines (National Cancer Institute)
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these 10 genes
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10 genes by gene family
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(show 10 source identifiers mapped to 10 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
143686
143686
SESN3
sestrin 3 [Source:HGNC Symbol;Acc:HGNC:23060]
23334
23334
SZT2
SZT2 subunit of KICSTOR complex [Source:HGN...
27244
27244
SESN1
sestrin 1 [Source:HGNC Symbol;Acc:HGNC:21595]
54468
54468
MIOS
meiosis regulator for oocyte development [S...
6396
6396
SEC13
SEC13 homolog, nuclear pore and COPII coat ...
652968
652968
CASTOR1
cytosolic arginine sensor for mTORC1 subuni...
729438
729438
CASTOR2
cytosolic arginine sensor for mTORC1 subuni...
79726
79726
WDR59
WD repeat domain 59 [Source:HGNC Symbol;Acc...
81929
81929
SEH1L
SEH1 like nucleoporin [Source:HGNC Symbol;A...
84219
84219
WDR24
WD repeat domain 24 [Source:HGNC Symbol;Acc...
Version history
2024.1.Hs: Updated to GO Release 2024-04-24.
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