Human Gene Set: GOCC_GATOR1_COMPLEX

For the Mouse gene set with the same name, see GOCC_GATOR1_COMPLEX

Standard name GOCC_GATOR1_COMPLEX
Systematic name M48605
Brief description A GTPase-activating protein (GAP) complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, the GATOR1 complex consists of DEPDC5, NPRL2, and NPRL3. In S. cerevisiae, this complex is referred to as SEACIT and contains the Iml1p, Npr2p, and Npr3p proteins. [GOC:krc, GOC:rb, PMID:21900499, PMID:23723238, PMID:23974112, PMID:25934700, PMID:28199306, PMID:29199950]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:1990130
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:1990130
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
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Version history 2024.1.Hs: Updated to GO Release 2024-04-24.

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