Human Gene Set: GOCC_EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_3_COMPLEX

For the Mouse gene set with the same name, see GOCC_EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_3_COMPLEX

Standard name GOCC_EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_3_COMPLEX
Systematic name M11411
Brief description A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs. [PMID:15904532]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:0005852
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0005852
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
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Version history 2024.1.Hs: Updated to GO Release 2024-04-24.

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