Human Gene Set: GOCC_DNA_REPLICATION_PREINITIATION_COMPLEX
For the Mouse gene set with the same name, see GOCC_DNA_REPLICATION_PREINITIATION_COMPLEX
Standard name
GOCC_DNA_REPLICATION_PREINITIATION_COMPLEX
Systematic name
M25733
Brief description
A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins might include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present. [GOC:bf, GOC:hjd, GOC:jl, GOC:pr, GOC:rb, GOC:vw, PMID:12694535, PMID:15194812, PMID:17230184]
Full description or abstract
Collection
C5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component
Source publication
Exact source
GO:0031261
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0031261
Filtered by similarity ?
Source species
Homo sapiens
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Human_NCBI_Gene_ID
Dataset references
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NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 13 genes
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13 genes by gene family
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(show 13 source identifiers mapped to 13 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
160728
160728
SLC5A8
solute carrier family 5 member 8 [Source:HGN...
23595
23595
ORC3
origin recognition complex subunit 3 [Source...
4171
4171
MCM2
minichromosome maintenance complex component...
4172
4172
MCM3
minichromosome maintenance complex component...
4173
4173
MCM4
minichromosome maintenance complex component...
4174
4174
MCM5
minichromosome maintenance complex component...
4175
4175
MCM6
minichromosome maintenance complex component...
4176
4176
MCM7
minichromosome maintenance complex component...
51659
51659
GINS2
GINS complex subunit 2 [Source:HGNC Symbol;A...
64785
64785
GINS3
GINS complex subunit 3 [Source:HGNC Symbol;A...
8318
8318
CDC45
cell division cycle 45 [Source:HGNC Symbol;A...
84296
84296
GINS4
GINS complex subunit 4 [Source:HGNC Symbol;A...
9837
9837
GINS1
GINS complex subunit 1 [Source:HGNC Symbol;A...
Version history
2024.1.Hs: Updated to GO Release 2024-04-24.
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