Human Gene Set: GOCC_DNA_DEPENDENT_PROTEIN_KINASE_DNA_LIGASE_4_COMPLEX
For the Mouse gene set with the same name, see GOCC_DNA_DEPENDENT_PROTEIN_KINASE_DNA_LIGASE_4_COMPLEX
Standard name
GOCC_DNA_DEPENDENT_PROTEIN_KINASE_DNA_LIGASE_4_COMPLEX
Systematic name
M48585
Brief description
A large protein complex which is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs), the DNA end-binding heterodimer Ku, the nuclear phosphoprotein XRCC4 or a homolog thereof, and DNA ligase IV. [GOC:jl, GOC:mah, PMID:10854421, PMID:12235392, PMID:17072889]
Full description or abstract
Collection
C5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component
Source publication
Exact source
GO:0005958
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0005958
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Source species
Homo sapiens
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Human_NCBI_Gene_ID
Dataset references
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these 7 genes
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7 genes by gene family
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(show 7 source identifiers mapped to 7 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
2547
2547
XRCC6
X-ray repair cross complementing 6 [Source:HGNC...
3981
3981
LIG4
DNA ligase 4 [Source:HGNC Symbol;Acc:HGNC:6601]
5591
5591
PRKDC
protein kinase, DNA-activated, catalytic subuni...
7518
7518
XRCC4
X-ray repair cross complementing 4 [Source:HGNC...
7520
7520
XRCC5
X-ray repair cross complementing 5 [Source:HGNC...
79840
79840
NHEJ1
non-homologous end joining factor 1 [Source:HGN...
91419
91419
ATP23
ATP23 metallopeptidase and ATP synthase assembl...
Version history
2024.1.Hs: Updated to GO Release 2024-04-24.
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