A protein complex that is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and the DNA end-binding heterodimer Ku. [GOC:mah, PMID:10854421, PMID:12235392]
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C5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component