Human Gene Set: GOCC_COHESIN_COMPLEX

For the Mouse gene set with the same name, see GOCC_COHESIN_COMPLEX

Standard name

GOCC_COHESIN_COMPLEX

Systematic name

M17737

Brief description

A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3). [GOC:jl, GOC:sp, GOC:vw, PMID:9887095]

Full description or abstract

Collection

C5: Ontology
GO: Gene Ontology
GO:CC: GO Cellular Component

Source publication

Exact source

GO:0008278

Related gene sets

External links

http://amigo.geneontology.org/amigo/term/GO:0008278

Filtered by similarity ?

Source species

Homo sapiens