Human Gene Set: GOCC_BRCA1_C_COMPLEX

For the Mouse gene set with the same name, see GOCC_BRCA1_C_COMPLEX

Standard name GOCC_BRCA1_C_COMPLEX
Systematic name M43129
Brief description A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint. [GOC:mah, PMID:15485915, PMID:16391231]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:0070533
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0070533
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
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Version history 2024.1.Hs: Updated to GO Release 2024-04-24.

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