Human Gene Set: GOCC_BRCA1_A_COMPLEX

For the Mouse gene set with the same name, see GOCC_BRCA1_A_COMPLEX

Standard name GOCC_BRCA1_A_COMPLEX
Systematic name M25890
Brief description A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites. [GOC:mah, PMID:19261749]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:0070531
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0070531
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 8 genes
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Version history 2024.1.Hs: Updated to GO Release 2024-04-24.

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