Human Gene Set: GOCC_AP_2_ADAPTOR_COMPLEX

Standard name

GOCC_AP_2_ADAPTOR_COMPLEX

Systematic name

M45964

Brief description

A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle, and the cargo receptors during receptor/clathrin mediated endocytosis. Vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC). [GOC:mah, PMID:10611976, PMID:21097499, PMID:22022230, PMID:24322426]

Full description or abstract

Collection

C5: Ontology
GO: Gene Ontology
GO:CC: GO Cellular Component

Source publication

Exact source

GO:0030122

Related gene sets

External links

http://amigo.geneontology.org/amigo/term/GO:0030122

Filtered by similarity ?

(show 1 similar ontology term(s) from the external resource)

Source species