Human Gene Set: GOCC_ANAPHASE_PROMOTING_COMPLEX

For the Mouse gene set with the same name, see GOCC_ANAPHASE_PROMOTING_COMPLEX

Standard name GOCC_ANAPHASE_PROMOTING_COMPLEX
Systematic name M17133
Brief description A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B. [GOC:jh, GOC:vw, PMID:10465783, PMID:10611969]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:0005680
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0005680
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
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NCI-60 cell lines (National Cancer Institute)
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Version history 2024.1.Hs: Updated to GO Release 2024-04-24.

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