A cyclic series of interconversions involving S-adenosylmethionine, S-adenosyl-L-homocysteine, L-cysteine, and L-methionine. Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of methionine. [GOC:mah, MetaCyc:PWY-5041]
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C5: Ontology GO: Gene Ontology GO:BP: GO Biological Process