Human Gene Set: GOBP_SEQUESTERING_OF_BMP_IN_EXTRACELLULAR_MATRIX
Standard name
GOBP_SEQUESTERING_OF_BMP_IN_EXTRACELLULAR_MATRIX
Systematic name
M42766
Brief description
Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins. [GOC:BHF, PMID:20855508]
Full description or abstract
Collection
C5: Ontology GO: Gene Ontology GO:BP: GO Biological Process