Human Gene Set: GOBP_RNA_POLYMERASE_I_PREINITIATION_COMPLEX_ASSEMBLY
Standard name
GOBP_RNA_POLYMERASE_I_PREINITIATION_COMPLEX_ASSEMBLY
Systematic name
M22167
Brief description
The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC) (which includes including UBF, SL1, RRN3 and TBP in human). The PIC engages RNA polymerase I on its DNA template strand and sparks polymerization of the first few RNA nucleotides. [GOC:txnOH, PMID:14969726]
Full description or abstract
Collection
C5: Ontology GO: Gene Ontology GO:BP: GO Biological Process
Source publication
Exact source
GO:0001188
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0001188
Filtered by similarity ?
Source species
Homo sapiens
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Human_NCBI_Gene_ID
Dataset references
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NCI-60 cell lines (National Cancer Institute)
Advanced query
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these 11 genes
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11 genes by gene family
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(show 11 source identifiers mapped to 11 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
11176
11176
BAZ2A
bromodomain adjacent to zinc finger domain ...
54700
54700
RRN3
RRN3 homolog, RNA polymerase I transcriptio...
642623
642623
UBTFL1
upstream binding transcription factor like ...
643615
643615
UBTFL6
UBTF like 6 (pseudogene) [Source:HGNC Symbo...
64425
64425
POLR1E
RNA polymerase I subunit E [Source:HGNC Sym...
6597
6597
SMARCA4
SWI/SNF related, matrix associated, actin d...
6598
6598
SMARCB1
SWI/SNF related, matrix associated, actin d...
6908
6908
TBP
TATA-box binding protein [Source:HGNC Symbo...
7343
7343
UBTF
upstream binding transcription factor [Sour...
9013
9013
TAF1C
TATA-box binding protein associated factor,...
9014
9014
TAF1B
TATA-box binding protein associated factor,...
Version history
2024.1.Hs: Updated to GO Release 2024-04-24.
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