Human Gene Set: GOBP_RELAXATION_OF_VASCULAR_ASSOCIATED_SMOOTH_MUSCLE

For the Mouse gene set with the same name, see GOBP_RELAXATION_OF_VASCULAR_ASSOCIATED_SMOOTH_MUSCLE

Standard name

GOBP_RELAXATION_OF_VASCULAR_ASSOCIATED_SMOOTH_MUSCLE

Systematic name

M40471

Brief description

A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity. [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:dph, GOC:rph, GOC:TermGenie, PMID:15867178, PMID:19996365, PMID:27389411]

Full description or abstract

Collection

C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process

Source publication

Exact source

GO:0060087

Related gene sets

External links

http://amigo.geneontology.org/amigo/term/GO:0060087

Filtered by similarity ?

Source species

Homo sapiens