Human Gene Set: GOBP_REGULATORY_NCRNA_MEDIATED_GENE_SILENCING

For the Mouse gene set with the same name, see GOBP_REGULATORY_NCRNA_MEDIATED_GENE_SILENCING

Standard name GOBP_REGULATORY_NCRNA_MEDIATED_GENE_SILENCING
Systematic name M42718
Brief description A process in which an regulatory non-coding RNA molecule reduces expression of target genes. This can occur pre-transcriptionally by assembly of heterochromatin and prevention of transcription or co- or post-transcriptionally by targeting RNAs for degradation or by interfering with splicing or translation. This process starts once the inhibitory RNA molecule has been transcribed, and includes processing of the RNA such as cleavage, modifications, transport from the nucleus to the cytoplasm, loading onto the RISC complex, and the effect on transcription or translation. [PMID:15020054]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:BP: GO Biological Process
Source publication  
Exact source GO:0031047
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0031047
Filtered by similarity ? (show 3 similar ontology term(s) from the external resource)
Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references  
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GTEx compendium
Human tissue compendium (Novartis)
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NCI-60 cell lines (National Cancer Institute)
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Version history 2024.1.Hs: Updated to GO Release 2024-04-24.

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