Human Gene Set: GOBP_HYPOXIA_INDUCIBLE_FACTOR_1ALPHA_SIGNALING_PATHWAY

For the Mouse gene set with the same name, see GOBP_HYPOXIA_INDUCIBLE_FACTOR_1ALPHA_SIGNALING_PATHWAY

Standard name

GOBP_HYPOXIA_INDUCIBLE_FACTOR_1ALPHA_SIGNALING_PATHWAY

Systematic name

M24770

Brief description

The series of molecular signals mediated by hypoxia-inducible factor (HIF1) in response to lowered oxygen levels (hypoxia). Under hypoxic conditions, the oxygen-sensitive alpha-subunit of hypoxia-inducible factor (HIF)-1 dimerizes with a HIF1-beta subunit (also called ARNT or aryl-hydrocarbon-receptor nuclear translocator), translocates to the nucleus and activates transcription of genes whose products participate in responding to hypoxia. [GOC:bf, GOC:jc, http://www.sabiosciences.com/pathway.php?sn=HIF1Alpha_Pathway]

Full description or abstract

Collection

C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process

Source publication

Exact source

GO:0097411

Related gene sets

External links

http://amigo.geneontology.org/amigo/term/GO:0097411

Filtered by similarity ?

Source species

Homo sapiens