Human Gene Set: GOBP_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY

For the Mouse gene set with the same name, see GOBP_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY

Standard name GOBP_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY
Systematic name M11317
Brief description The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered. [GOC:mtg_apoptosis, GOC:yaf, PMID:17340152]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:BP: GO Biological Process
Source publication  
Exact source GO:0097191
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0097191
Filtered by similarity ?
Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 230 genes
Gene families ? Categorize these 230 genes by gene family
Show members (show 230 source identifiers mapped to 230 genes)
Version history 2024.1.Hs: Updated to GO Release 2024-04-24.

See MSigDB license terms here. Please note that certain gene sets have special access terms.