Human Gene Set: GOBP_ERROR_PRONE_TRANSLESION_SYNTHESIS

For the Mouse gene set with the same name, see GOBP_ERROR_PRONE_TRANSLESION_SYNTHESIS

Standard name GOBP_ERROR_PRONE_TRANSLESION_SYNTHESIS
Systematic name M14864
Brief description The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions and causes an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically targeted to DNA template damage sites, but it can also produce mutations at undamaged sites. [GOC:elh, GOC:jl, PMID:11485998]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:BP: GO Biological Process
Source publication  
Exact source GO:0042276
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0042276
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
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Version history 2024.1.Hs: Updated to GO Release 2024-04-24.

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