Human Gene Set: GOBP_DOUBLE_STRAND_BREAK_REPAIR_VIA_ALTERNATIVE_NONHOMOLOGOUS_END_JOINING

For the Mouse gene set with the same name, see GOBP_DOUBLE_STRAND_BREAK_REPAIR_VIA_ALTERNATIVE_NONHOMOLOGOUS_END_JOINING

Standard name

GOBP_DOUBLE_STRAND_BREAK_REPAIR_VIA_ALTERNATIVE_NONHOMOLOGOUS_END_JOINING

Systematic name

M48514

Brief description

An instance of double-strand break repair via nonhomologous end joining that is independent of factors important for V(D)J recombination (as opposed to classical nonhomologous end joining). It often results in a deletion with microhomology (i.e. 5-25bp homology) at the repair junction. Among different subclasses of nonhomologous end joining (NHEJ), alternative NHEJ appears to play a significant role in the etiology of mutations that arise during cancer development and treatment. [GOC:rph, PMID:18584027, PMID:21655080, Wikipedia:Microhomology-mediated_end_joining]

Full description or abstract

Collection

C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process

Source publication

Exact source

GO:0097681

Related gene sets

External links

http://amigo.geneontology.org/amigo/term/GO:0097681

Filtered by similarity ?

Source species

Homo sapiens