Human Gene Set: GOBP_CGAS_STING_SIGNALING_PATHWAY

For the Mouse gene set with the same name, see GOBP_CGAS_STING_SIGNALING_PATHWAY

Standard name GOBP_CGAS_STING_SIGNALING_PATHWAY
Systematic name M48526
Brief description The series of molecular signals initiated by the binding of a double-stranded DNA or RNA from another organism to cytosolic cyclic GMP-AMP (cGAMP) synthase (cGAS) that activates innate immune responses through production of the second messenger cGAMP, which activates the adaptor STING. [PMID:27648547, PMID:34261127, PMID:34261128]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:BP: GO Biological Process
Source publication  
Exact source GO:0140896
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0140896
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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Version history 2025.1.Hs: Updated to GO Release 2025-03-16.

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