Human Gene Set: GOBP_7_METHYLGUANOSINE_RNA_CAPPING
Standard name
GOBP_7_METHYLGUANOSINE_RNA_CAPPING
Systematic name
M45080
Brief description
The sequence of enzymatic reactions by which the RNA 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript. Additional methylation can occur on the ribose sugars of the first and second nucleotides adjacent to the m7G nRNA cap. These methylations are often referred to as N6,2'-O-dimethyladenosine (m6,2A) and N6,2'-O-dimethylguanosine (m6,2G), respectively. [GOC:vw, PMID:9266685]
Full description or abstract
Collection
C5: Ontology GO: Gene Ontology GO:BP: GO Biological Process
