Human Gene Set: FAN_OVARY_CL9_PUTATIVE_APOPTOTIC_ENDOTHELIAL_CELL


Standard name FAN_OVARY_CL9_PUTATIVE_APOPTOTIC_ENDOTHELIAL_CELL
Systematic name M41711
Brief description We identified three separate clusters (CL) of endothelial cells (CL7, CL9, CL16) expressing markers associated with lymph and blood vascular system (such as PECAM1, CD34, CTGF), but also associated with remodeling and inflammatory response (such as TXNIP, ANGPT2) (Fig. 3a-d). The DEGs of CL7 (such as CCL14, SOCS3, EGFL7) and CL16 (such as CCL21, TFF3) are linked to angiogenesis and lymphatics, respectively, while DEGs of CL9 (TM4SF1, NMMT) were more related to regulation of apoptosis (Fig. 3c, d).
Full description or abstract  
Collection C8: Cell Type Signature
Source publication Pubmed 31320652   Authors: Fan X,Bialecka M,Moustakas I,Lam E,Torrens-Juaneda V,Borggreven NV,Trouw L,Louwe LA,Pilgram GSK,Mei H,van der Westerlaken L,Chuva de Sousa Lopes SM
Exact source Supplementary Data 2 (complete underlying data received from authors), avg_logFC > 0.25, p_val_adj <0.05
Related gene sets (show 18 additional gene sets from the source publication)

(show 119 gene sets from the same authors)
External links https://doi.org/10.1038/s41467-019-11036-9
Filtered by similarity ?
Source species Homo sapiens
Contributed by Anthony Castanza (MSigDB Team)
Source platform or
identifier namespace		 HUMAN_GENE_SYMBOL
Dataset references (show 1 datasets)
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 365 genes
Gene families ? Categorize these 365 genes by gene family
Show members (show 366 source identifiers mapped to 365 genes)
Version history 7.3: First Introduced.

See MSigDB license terms here. Please note that certain gene sets have special access terms.