Human Gene Set: FAN_OVARY_CL0_XBP1_SELK_HIGH_STROMAL_CELL


Standard name FAN_OVARY_CL0_XBP1_SELK_HIGH_STROMAL_CELL
Systematic name M41702
Brief description Most stromal cells from selectable follicle C clustered in CL1 (Fig. 3a). Although stromal clusters (CL0, CL1) showed high expression of GNL3 and ARID5B (Fig. 8d), CL0 expressed high levels of XBP1 and SELK (Fig. 8e), both involved in endoplasmic reticulum (ER)-stress-induced apoptosis, whereas CL1 expressed high levels of GPRC5A and TNFRS12A (Fig. 8f).
Full description or abstract  
Collection C8: Cell Type Signature
Source publication Pubmed 31320652   Authors: Fan X,Bialecka M,Moustakas I,Lam E,Torrens-Juaneda V,Borggreven NV,Trouw L,Louwe LA,Pilgram GSK,Mei H,van der Westerlaken L,Chuva de Sousa Lopes SM
Exact source Supplementary Data 2 (complete underlying data received from authors), avg_logFC > 0.25, p_val_adj <0.05
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External links https://doi.org/10.1038/s41467-019-11036-9
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Source species Homo sapiens
Contributed by Anthony Castanza (MSigDB Team)
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