Human Gene Set: E2F1_UP.V1_DN


Standard name E2F1_UP.V1_DN
Systematic name M2630
Brief description Genes down-regulated in mouse fibroblasts over-expressing E2F1 [GeneID=1869] gene.
Full description or abstract Identification of E2F1-regulated genes that modulate the transition from quiescence into DNA synthesis, or have roles in apoptosis, signal transduction, membrane biology, and transcription repression.
Collection C6: Oncogenic Signature
Source publication Pubmed 11888208   Authors: Ma Y,Croxton R,Moorer RL Jr,Cress WD
Exact source E2F1 vs BetaGal; bottom 200 genes (diff. of means)
Related gene sets (show 1 additional gene sets from the source publication)

(show 96 gene sets from any of these authors)
External links
Filtered by similarity ?
Source species Mus musculus
Contributed by Pablo Tamayo (Broad Institute)
Source platform or
identifier namespace		 HUMAN_GENE_SYMBOL
Dataset references (show 1 datasets)
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 187 genes
Gene families ? Categorize these 187 genes by gene family
Show members (show 200 source identifiers mapped to 187 genes)
Version history  


Creative Commons Attribution 4.0 International License (CC-BY-4.0)

The contents of this gene set are protected by copyright (c) 2004-2026 Broad Institute, Inc., Massachusetts Institute of Technology, and Regents of the University of California, subject to the terms and conditions of the Creative Commons Attribution 4.0 International License.

See the full MSigDB license terms here.