Human Gene Set: DNA_DAMAGE_CHECKPOINT
Standard name
DNA_DAMAGE_CHECKPOINT
Systematic name
M7533
Brief description
Genes annotated by the GO term GO:0000077. A signal transduction pathway, induced by DNA damage, that blocks cell cycle progression (in G1, G2 or metaphase) or slows the rate at which S phase proceeds.
Full description or abstract
Collection
ARCHIVED: Archived Founder gene sets that are referenced by current Hallmarks C5_GO: ARCHIVED Gene Ontology C5_GO:BP: ARCHIVED GO Biological Process
Source publication
Exact source
GO:0000077
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0000077
Filtered by similarity ?
Source species
Homo sapiens
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
HUMAN_GENE_SYMBOL
Dataset references
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format: grp | gmt | xml | json | TSV metadata
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(show 20 source identifiers mapped to 20 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
ATR
545
ATR
ATR serine/threonine kinase [Source:HGNC Sym...
ATRIP
84126
ATRIP
ATR interacting protein [Source:HGNC Symbol;...
BRSK1
84446
BRSK1
BR serine/threonine kinase 1 [Source:HGNC Sy...
CCNA2
890
CCNA2
cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578]
CHEK1
1111
CHEK1
checkpoint kinase 1 [Source:HGNC Symbol;Acc:...
CHEK2
11200
CHEK2
checkpoint kinase 2 [Source:HGNC Symbol;Acc:...
FOXN3
1112
FOXN3
forkhead box N3 [Source:HGNC Symbol;Acc:HGNC...
GML
2765
GML
glycosylphosphatidylinositol anchored molecu...
HUS1
3364
HUS1
HUS1 checkpoint clamp component [Source:HGNC...
NAE1
8883
NAE1
NEDD8 activating enzyme E1 subunit 1 [Source...
NBN
4683
NBN
nibrin [Source:HGNC Symbol;Acc:HGNC:7652]
NEK11
79858
NEK11
NIMA related kinase 11 [Source:HGNC Symbol;A...
PCBP4
57060
PCBP4
poly(rC) binding protein 4 [Source:HGNC Symb...
PML
5371
PML
PML nuclear body scaffold [Source:HGNC Symbo...
RAD1
5810
RAD1
RAD1 checkpoint DNA exonuclease [Source:HGNC...
RAD17
5884
RAD17
RAD17 checkpoint clamp loader component [Sou...
RAD9A
5883
RAD9A
RAD9 checkpoint clamp component A [Source:HG...
RINT1
60561
RINT1
RAD50 interactor 1 [Source:HGNC Symbol;Acc:H...
TRIAP1
51499
TRIAP1
TP53 regulated inhibitor of apoptosis 1 [Sou...
ZAK
51776
MAP3K20
mitogen-activated protein kinase kinase kina...
Version history
5.2: Archived
Gene set replaced by GOBP_DNA_INTEGRITY_CHECKPOINT_SIGNALING
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