Human Gene Set: CORONEL_RFX7_DIRECT_TARGETS_UP


Standard name CORONEL_RFX7_DIRECT_TARGETS_UP
Systematic name M42500
Brief description Direct target genes of the transcription factor and emerging tumor suppressor RFX7.
Full description or abstract RFX7 is an emerging tumor suppressor that is activated in response to p53 and stress. Integrative analysis of the RFX7 DNA binding landscape (ChIP-seq) and the RFX7-regulated transcriptome (RNA-seq) in three distinct cell systems revealed direct RFX7 target genes. Direct RFX7 target genes identified in at least two of the three cell lines comprise a set of 57 genes.
Collection C2: Curated
      CGP: Chemical and Genetic Perturbations
Source publication Pubmed 34197623   Authors: Coronel L,Riege K,Schwab K,Förste S,Häckes D,Semerau L,Bernhart SH,Siebert R,Hoffmann S,Fischer M
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Source species Homo sapiens
Contributed by Martin Fischer (Leibniz Institute on Aging ? Fritz Lipmann Institute (FLI))
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identifier namespace		 HUMAN_GENE_SYMBOL
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Version history 7.5: First Introduced.

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