Human Gene Set: BIOCARTA_TNFR1_PATHWAY

For the Mouse gene set with the same name, see BIOCARTA_TNFR1_PATHWAY

Standard name BIOCARTA_TNFR1_PATHWAY
Systematic name M3618
Brief description TNFR1 Signaling Pathway
Full description or abstract TNFR1 (a.k.a. p55, CD120a) is the receptor for TNF(alpha) and also will bind TNF(beta). Upon binding TNF(alpha) a TNFR1+ cell is triggered to undergo apoptosis. This critical regulatory process is accomplished by activating the proteolytic caspase cascade that results in the degradation of many critical cellular proteins.
Collection C2: Curated
      CP: Canonical Pathways
            CP:BIOCARTA: BioCarta Pathways
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External links https://data.broadinstitute.org/gsea-msigdb/msigdb/biocarta/human/h_tnfr1Pathway.gif
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Source species Homo sapiens
Contributed by BioCarta
Source platform or
identifier namespace		 Human_RefSeq
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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Version history 7.0: Changed members. Upgraded to final version of Biocarta.

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