Human Gene Set: BIOCARTA_IL2_PATHWAY

For the Mouse gene set with the same name, see BIOCARTA_IL2_PATHWAY

Standard name BIOCARTA_IL2_PATHWAY
Systematic name M7747
Brief description IL 2 signaling pathway
Full description or abstract Interleukin 2 (IL-2) is a potent cytokine that can lead to cellular activation and proliferation. IL-2 Receptors are found on activated B-Cells, LPS treated Monocytes, and many T cells. The receptor is formed from three chains alpha (CD25), beta (CD122), and gamma (CD132). Primary signaling is through the JAK/Stat pathway and MAPKs.
Collection C2: Curated
      CP: Canonical Pathways
            CP:BIOCARTA: BioCarta Pathways
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External links https://data.broadinstitute.org/gsea-msigdb/msigdb/biocarta/human/h_il2Pathway.gif
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Source species Homo sapiens
Contributed by BioCarta
Source platform or
identifier namespace
HUMAN_SEQ_ACCESSION
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NCI-60 cell lines (National Cancer Institute)
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Version history 7.0: Changed members. Upgraded to final version of Biocarta.

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