Human Gene Set: ALK_DN.V1_UP


Standard name ALK_DN.V1_UP
Systematic name M2774
Brief description Genes up-regulated in DAOY cells (medulloblastoma) upon knockdown of ALK [GeneID=238] gene by RNAi.
Full description or abstract Analysis of DAOY medulloblastoma cells following RNAi knockdown of Alk.
Collection C6: Oncogenic Signature
Source publication Pubmed 17452456   Authors: Wiederschain D,Chen L,Johnson B,Bettano K,Jackson D,Taraszka J,Wang YK,Jones MD,Morrissey M,Deeds J,Mosher R,Fordjour P,Lengauer C,Benson JD
Exact source Alk shRNA vs Wild Type; top 150 genes (diff. of means)
Related gene sets (show 8 additional gene sets from the source publication)

(show 30 gene sets from the same authors)
External links
Filtered by similarity ?
Source species Homo sapiens
Contributed by Pablo Tamayo (Broad Institute)
Source platform or
identifier namespace		 HUMAN_GENE_SYMBOL
Dataset references (show 1 datasets)
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 141 genes
Gene families ? Categorize these 141 genes by gene family
Show members (show 150 source identifiers mapped to 141 genes)
Version history  

See MSigDB license terms here. Please note that certain gene sets have special access terms.