Human Gene Set: HOUNKPE_HOUSEKEEPING_GENES

For the Mouse gene set with the same name, see HOUNKPE_HOUSEKEEPING_GENES

Standard name HOUNKPE_HOUSEKEEPING_GENES
Systematic name M42508
Brief description List of 1130 human and mouse housekeeping genes. This list shows the overlap of human genes stably expressed across 52 tissues and cells types and mouse genes with at least one of their transcripts expressed across 14 tissues and cells types.
Full description or abstract Housekeeping (HK) genes are constitutively expressed genes that are required for the maintenance of basic cellular functions. Despite their importance in the calibration of gene expression, as well as the understanding of many genomic and evolutionary features, important discrepancies have been observed in studies that previously identified these genes. Here, we present Housekeeping and Reference Transcript Atlas (HRT Atlas v1.0, www.housekeeping.unicamp.br) a web-based database which addresses some of the previously observed limitations in the identification of these genes and offers a more accurate database of human HK genes and transcripts. The database was generated by mining massive human and mouse RNA-seq data sets, including 11 281 and 507 high-quality RNA-seq samples from 52 human non-disease tissues/cells and 14 healthy tissues/cells of C57BL/6 wild type mouse, respectively. Overall, 2176 housekeeping genes have been identified in this study.
Collection C2: Curated
      CGP: Chemical and Genetic Perturbations
Source publication Pubmed 32663312   Authors: Hounkpe BW,Chenou F,de Lima F,De Paula EV
Exact source https://housekeeping.unicamp.br/Human_Mouse_Common.csv
Related gene sets  
External links https://housekeeping.unicamp.br/?about
Filtered by similarity ?
Source species Homo sapiens
Contributed by Bidossessi Wilfried Hounkpe (Unicamp)
Source platform or
identifier namespace		 HUMAN_GENE_SYMBOL
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 1129 genes
Gene families ? Categorize these 1129 genes by gene family
Show members (show 1129 source identifiers mapped to 1129 genes)
Version history 7.5: First Introduced.

See MSigDB license terms here. Please note that certain gene sets have special access terms.