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Human Gene Set: REACTOME_SIGNALING_BY_CTNNB1_PHOSPHO_SITE_MUTANTS
Standard name
REACTOME_SIGNALING_BY_CTNNB1_PHOSPHO_SITE_MUTANTS
Systematic name
M27407
Brief description
Signaling by CTNNB1 phospho-site mutants
Full description or abstract
Collection
C2: Curated
CP: Canonical Pathways
CP:REACTOME: Reactome Pathways
Source publication
Exact source
R-HSA-4839743
Related gene sets
External links
https://www.reactome.org/content/detail/R-HSA-4839743
Filtered by similarity
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11 similar pathway(s) from the external resource)
External ID
External Name
R-HSA-4839735
Signaling by AXIN mutants
R-HSA-4839744
Signaling by APC mutants
R-HSA-4839748
Signaling by AMER1 mutants
R-HSA-5339716
Signaling by GSK3beta mutants
R-HSA-5358747
CTNNB1 S33 mutants aren't phosphorylated
R-HSA-5358749
CTNNB1 S37 mutants aren't phosphorylated
R-HSA-5358751
CTNNB1 S45 mutants aren't phosphorylated
R-HSA-5358752
CTNNB1 T41 mutants aren't phosphorylated
R-HSA-5467337
APC truncation mutants have impaired AXIN binding
R-HSA-5467340
AXIN missense mutants destabilize the destruction complex
R-HSA-5467348
Truncations of AMER1 destabilize the destruction complex
Source species
Homo sapiens
Contributed by
Reactome
Source platform or
identifier namespace
Human_Ensembl_Gene_ID
Dataset references
Download gene set
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grp
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
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Gene families
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Show members
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15 source identifiers mapped to 15 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
ENSG00000066027
5525
PPP2R5A
protein phosphatase 2 regulatory s...
ENSG00000068971
5526
PPP2R5B
protein phosphatase 2 regulatory s...
ENSG00000078304
5527
PPP2R5C
protein phosphatase 2 regulatory s...
ENSG00000082701
2932
GSK3B
glycogen synthase kinase 3 beta [S...
ENSG00000103126
8312
AXIN1
axin 1 [Source:HGNC Symbol;Acc:HGN...
ENSG00000104695
5516
PPP2CB
protein phosphatase 2 catalytic su...
ENSG00000105568
5518
PPP2R1A
protein phosphatase 2 scaffold sub...
ENSG00000112640
5528
PPP2R5D
protein phosphatase 2 regulatory s...
ENSG00000113575
5515
PPP2CA
protein phosphatase 2 catalytic su...
ENSG00000113712
1452
CSNK1A1
casein kinase 1 alpha 1 [Source:HG...
ENSG00000134982
324
APC
APC regulator of WNT signaling pat...
ENSG00000137713
5519
PPP2R1B
protein phosphatase 2 scaffold sub...
ENSG00000154001
5529
PPP2R5E
protein phosphatase 2 regulatory s...
ENSG00000168036
1499
CTNNB1
catenin beta 1 [Source:HGNC Symbol...
ENSG00000184675
139285
AMER1
APC membrane recruitment protein 1...
Version history
2024.1.Hs: Updated to Reactome v89
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