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Human Gene Set: KEGG_MEDICUS_REFERENCE_IL1_IL1R_P38_SIGNALING_PATHWAY
Standard name
KEGG_MEDICUS_REFERENCE_IL1_IL1R_P38_SIGNALING_PATHWAY
Systematic name
M47470
Brief description
Pathway Definition from KEGG: IL1 -> IL1R -> MYD88 -> IRAK1/4 -> TRAF6 -> TAB1/2/3 -> TAK1 -> MKK3/6 -> MAPK14 -> MK2 -| TTP
Full description or abstract
IL1-IL1R-p38 signaling pathway. Pathway ID: N00186. Pathway type: Reference. Pathway class: nt06526 MAPK signaling.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N00186
Related gene sets
External links
https://www.kegg.jp/entry/N00186
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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xml
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json
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 17 genes
Gene families
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these 17 genes by gene family
Show members
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17 source identifiers mapped to 17 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
10454
10454
TAB1
TGF-beta activated kinase 1 (MAP3K7) bindi...
1432
1432
MAPK14
mitogen-activated protein kinase 14 [Sourc...
23118
23118
TAB2
TGF-beta activated kinase 1 (MAP3K7) bindi...
257397
257397
TAB3
TGF-beta activated kinase 1 (MAP3K7) bindi...
3552
3552
IL1A
interleukin 1 alpha [Source:HGNC Symbol;Ac...
3553
3553
IL1B
interleukin 1 beta [Source:HGNC Symbol;Acc...
3554
3554
IL1R1
interleukin 1 receptor type 1 [Source:HGNC...
3556
3556
IL1RAP
interleukin 1 receptor accessory protein [...
3654
3654
IRAK1
interleukin 1 receptor associated kinase 1...
4615
4615
MYD88
MYD88 innate immune signal transduction ad...
51135
51135
IRAK4
interleukin 1 receptor associated kinase 4...
5606
5606
MAP2K3
mitogen-activated protein kinase kinase 3 ...
5608
5608
MAP2K6
mitogen-activated protein kinase kinase 6 ...
6885
6885
MAP3K7
mitogen-activated protein kinase kinase ki...
7189
7189
TRAF6
TNF receptor associated factor 6 [Source:H...
7538
7538
ZFP36
ZFP36 ring finger protein [Source:HGNC Sym...
9261
9261
MAPKAPK2
MAPK activated protein kinase 2 [Source:HG...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-264
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